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Bioinformatics Software

This code may be freely used for all non-commercial purposes.
(c) Copyright, 2005 by Professor Alexander Zelikovsky
Department of Computer Science, Georgia State University
Atlanta, GA 30303 (404) 651-0676
alexz@cs.gsu.edu http://www.cs.gsu.edu/~cscazz/

Trio Phasing:  Frequently case/control genotype data represents family trios consisting of two parents and one offspring. The trio phasing project develops a satisfactory method for phasing family trio data.

Disease Association: This project explores disease susceptibility prediction on genotype/haplotype data.

2SNP:  SCALABLE PHASING METHOD BASED ON 2-SNP HAPLOTYPES. New phasing is based on statistically significant LD and deviation from Hardy-Weinberg equilibrium. On datasets across 69 regions from HapMap 2SNP is 3-4 orders of magnitude faster and usually outperforms HAPLOTYPER, GERBIL and matches PHASE.

Tagging: Tag Selection based on SNP Multivariate Linear Regression.

DACS: Disease Association Combinatorial Search software searches for statistically significant multi-SNP combinations associated with a disease.

MetNetAligner: Web service tool for

·        matching metabolic pathways/networks

·        identifying pathway holes  (missing enzymes) and  suggesting plausible candidates

·        and finding network motifs

 

ViSpA: Viral Spectrum Assembler implements a novel viral assembling and frequency estimation methods. This software uses a simple error correction, viral variants assembling based on maximum-bandwidth paths in weighted read graphs and frequency estimation via Expectation Maximization on all reads.


Contact

Dr. Alex Zelikovsky
Office: 1443, Peachtree Street 34
Department of Computer Science
Georgia State University
Atlanta, GA 30303-3086
Phone: (404) 651-0676
Fax: (815) 642-0052
Email: alexz@cs.gsu.edu

 


Acknowledgment

 This website is partially supported by National Science Foundation under Grant No. 0429735.